2024/05: Two patents issued for parametric PET techniques with clinical applications

UC Davis has received two patents on parametric PET techniques that explore the molecular transport properties of radiotracers for clinical applications after four years since filing. One patent (inventors: Guobao Wang, Souvik Sarkar, and Ramsey Badawi) is on a liver parametric PET method for measuring hepatic inflammation in fatty liver disease. In combination with CT for measuring steatosis, the liver parametric PET/CT method can be used to noninvasively diagnose and characterize metabolic dysfunction-associated steatohepatitis (MASH). The other patent (inventor: Guobao Wang) is for a technique that uses high-temporal resolution kinetic modeling to enable widely used radiotracers (e.g., 18F-FDG) for quantitative measurement of blood flow, enabling single-tracer multiparametric PET imaging for several clinical applications.