UC Davis has received two patents on parametric PET techniques that explore the molecular transport properties of radiotracers for clinical applications after four years since filing. One patent (inventors: Guobao Wang, Souvik Sarkar, and Ramsey Badawi) is on a liver parametric PET method for measuring hepatic inflammation in fatty liver disease. In combination with CT for measuring steatosis, the liver parametric PET/CT method can be used to noninvasively diagnose and characterize metabolic dysfunction-associated steatohepatitis (MASH). The other patent (inventor: Guobao Wang) is for a technique that uses high-temporal resolution kinetic modeling to enable widely used radiotracers (e.g., 18F-FDG) for quantitative measurement of blood flow, enabling single-tracer multiparametric PET imaging for several clinical applications.
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