Congratulations to Dr. Kevin Chung on having his paper (preprint) accepted by Nature Communications! The paper focuses on imaging blood-brain barrier (BBB) permeability using high-temporal resolution dynamic PET enabled by EXPLORER and through advanced kinetic modeling. This method opens new directions to efficiently study the molecular permeability of the human BBB in vivo using the large catalog of available molecular PET tracers. Many potential applications can be further developed for imaging neurological and systemic diseases.

This paper marks a significant milestone in our lab’s long-term research efforts to explore the imaging of the molecular transport properties of radiotracers.

Kevin is jointly supervised by Dr. Guobao Wang and Dr. Simon Cherry. Also thanks to all collaborators for making this work possible.

Dr. Siqi Li received a two-year NIH/NIBIB R03 research award as Principal Investigator to develop the feasibility of Total-body PET Parametric Imaging using Relative Patlak Plot, also see the method described in his recent JNM paper. Congratulations to Siqi for your first grant!

Congratulations to Dr. Kevin Chung for receiving a prestigious two-year Postdoctoral Fellowship from the American Heart Association (AHA). His project will develop Multiparametric PET Imaging of the Heart-Brain Axis. Kevin is jointly supervised by Dr. Guobao Wang and Dr. Simon Cherry. His mentoring committee also includes cardiologist Dr. Javier Lopez and neuroimaging scientist Dr. Audrey Fan.

Congratulations to our graduate student Xiaoyu Duan for receiving the Runner-Up in the Best Student Paper competition at the IEEE Medical Imaging Conference (MIC) in Tampa, Florida. Her paper “Quantification of [18F]FDG Delivery Rate for Liver Inflammation using Shortened Dynamic PET Imaging Protocols” develops a practical approach for using dynamic FDG-PET to assess liver inflammation. Xiaoyu is jointly supervised by Dr.  Guobao Wang and Dr. Ramsey Badawi.

Our lab had a good showcase at the 2024 IEEE Medical Imaging Conference in Tampa, Florida. Dr. Siqi Li, Dr. Yansong Zhu, Dr. Kevin Chung, and graduate student Xiaoyu Duan reported their recent work on PET image reconstruction or kinetic modeling at the conference.

Congratulations to Dr. Kevin Chung for receiving the Best Presentation Award for his talk at the 2024 Total-Body PET Conference in Groningen, Netherlands! Kevin is jointly supervised by Dr. Simon Cherry.

Kevin J. Chung, Abhijit J. Chaudhari, Lorenzo Nardo, Terry Jones, Moon S. Chen Jr., Ramsey D. Badawi, Simon R. Cherry, Guobao Wang. Total-Body Perfusion Imaging with High Temporal Resolution Kinetic Modeling of Early Dynamic 18F-FDG PET. Total-Body PET 2024 Conference, Groningen, Netherlands, September 19-21, 2024.

Congratulations to Dr. Quyen Tran for his work receiving the Best Poster Award at the same conference!

Quyen Tran, Victoria Lyo, Karen E. Matsukuma, Michael T. Corwin, Benjamin A. Spencer, Valentina Medici, Terry Jones, Simon R. Cherry, Ramsey D. Badawi, Souvik Sarkar, and Guobao Wang. Total-body parametric PET with free-state tracer kinetic modeling: application to imaging of metabolic dysfunction-associated steatohepatitis (MASH) with 18F-FDG. Total-Body PET 2024 Conference, Groningen, Netherlands, September 19-21, 2024.

Congratulations to our graduate student Xiaoyu Duan for receiving the Best Abstract award submitted by a graduate student at the 2024 UC Davis Radiology Symposium.

Congratulations to Dr. Kevin Chung for receiving the Best Abstracts Award submitted by a postdoc or fellow. This is his second time winning this award.

Our lab will have three abstracts to present at the upcoming 2024 IEEE Medical Imaging Conference in Tampa.

Xiaoyu Duan, S Sarkar, V Lyo, S Romeo, K Matsukuma, V Medici, M Corwin, RD Badawi, and G. Wang. Quantification of 18F-FDG Delivery Rate for Liver Inflammation using Shortened Dynamic PET Imaging Protocols. 2024 IEEE Medical Imaging Conference, Tampa, Florida, Oct 30-Nov 2, 2024. Oral Presentation.

Kevin J. Chung, YG Abdelhafez, BA Spencer, T Jones, RD Badawi, SR Cherry, G Wang. Quantification and Identifiability of Molecular Blood-Brain Barrier Permeability-Surface Area with Total-Body Dynamic PET. 2024 IEEE Medical Imaging Conference, Tampa, Florida, Oct 30-Nov 2, 2024. Oral Presentation.

Siqi Li, BA Spencer, L Nardo, J Qi, SR Cherry, RD Badawi and G Wang. Dynamic PET Image Reconstruction Using Deep Kernel Pretraining from a Total-Body PET Dataset. 2024 IEEE Medical Imaging Conference, Tampa, Florida, Oct 30-Nov 2, 2024. Oral Presentation.

Dr. Siqi Li and Dr. Kevin Chung attended the SNMMI Annual Meeting in Toronto, June 8-11, 2024. Each of them presented their latest work on total-body PET kinetic modeling and parametric imaging.

Siqi Li, YG Abdelhafez, L Nardo, SR Cherry, RD Badawi, GB Wang.Total-body parametric imaging using relative Patlak plot with self-supervised deep learning noise reduction.2024 SNMMI Annual Meeting, Toronto, June 8-11, 2024

Kevin J. Chung, YG Abdelhafez, BA Spencer, T Jones, Q Tran, L Nardo, S Sarkar, V Medici, V Lyo, RD Badawi, SR Cherry, GB Wang. Single-tracer imaging of molecular blood-brain barrier permeability-surface area with total-body PET. 2024 SNMMI Annual Meeting, Toronto, June 8-11, 2024.

Photo credit: Dr. Lorenzo Nardo

Dr. Yiran Wang’s research on dynamic PET imaging of the dual-blood supply effect in lung tissue and lung tumors was featured in the Headlines of UC Davis Health News on June 7th:

“Lung cancer breakthroughs: New imaging technologies may change course for top cancer killer”

This was one of the works that Yiran had done during his Ph.D. research under the joint supervision of Dr. Guobao Wang and Dr. Simon R. Cherry. His paper is currently in press in the Journal of Nuclear Medicine. Congratulations, Yiran!